The main benefit of this nomogram is to provide informative support to urologists seeking to identify men with LUTS related to benign prostatic hyperplasia (BPH) and prostatic inflammation.1
Objectives and methodology1
The primary objective of PINS was to develop and validate a nomogram based on demographic and clinical characteristics to predict the presence of prostatic inflammation in men suffering from LUTS. This prospective, multicenter, non-interventional study included 423 men over 40 years, with an average age of 68.9 years, scheduled for prostatic surgery or transrectal ultrasound-guided prostatic biopsy across six centers in Southern Europe.
Key findings1
Analysis revealed several factors significantly associated with moderate to severe prostatic inflammation, including a prostate volume greater than 50 mL, a history of urinary tract infections, the presence of diabetes, the presence of leucocytes in urine, and a high IPSS storage score. The developed nomogram, based on these factors, demonstrated good predictive capacity with a concordance index of 0.71, suggesting its potential utility in clinical practice for identifying patients at risk of prostatic inflammation.
Clinical implications1
The nomogram developed from PINS has the potential to contribute to an individualized approach for men suffering from LUTS due to BPH, by predicting those who can present or be at risk of prostatic inflammation.
For detailed insights and more on the methodologies applied in this study, please refer to the full publication, Professor Stavros Gravas' “Development and validation of a clinical nomogram to predict prostatic inflammation in men with lower urinary tract symptoms”.